Caffeine acts on the central nervous system, the peripheral nervous system and skeletal muscle, which may have a beneficial effect on sports performance.
Caffeine and sports performance
Caffeine, consumed by approximately 80% of the world's population, is found in more than 60 types of plants, including coffee beans and tea leaves, which are its main dietary sources. Caffeine also forms part of the composition of certain drugs and supplements and is used by the food industry in the production of energy drinks. This compound is rapidly absorbed in the intestinal tract and metabolized in the liver to paraxanthine, theophylline and theobromine. The derived metabolites, together with caffeine itself, exert a significant effect on athletic performance.
During exercise, caffeine can enhance performance by decreasing glycogen utilization and increasing free fatty acid mobilization. It also acts as an adenosine receptor antagonist and increases dopamine availability, which improves alertness and motivation. In addition, caffeine has analgesic and anti-inflammatory properties, thus promoting post-exercise recovery.
Not all people respond equally to caffeine and show the same beneficial effects in sports practice. There are multiple factors that can interfere, such as, for example, the degree of training, caffeine tolerance and genetics.
Genes analyzed
Bibliography
Guest NS, VanDusseldorp TA, Nelson MT, et al. International society of sports nutrition position stand: caffeine and exercise performance. J Int Soc Sports Nutr. 2021 Jan 2;18(1):1.
Guest NS, Horne J, Vanderhout SM, et al. Sport Nutrigenomics: Personalized Nutrition for Athletic Performance. Front Nutr. 2019 Feb 19;6:8.
Pickering C, Grgic J. Caffeine and Exercise: What Next? Sports Med. 2019 Jul;49(7):1007-1030.
Martins GL, Guilherme JPLF, Ferreira LHB, et al. Caffeine and Exercise Performance: Possible Directions for Definitive Findings. Front Sports Act Living. 2020 Dec 11;2:574854.
Wang J, Dewi L, Peng Y, et al. Does ergogenic effect of caffeine supplementation depend on CYP1A2 genotypes? A systematic review with meta-analysis. J Sport Health Sci. 2023 Dec 28:S2095-2546(23)00131-X.